top of page
AI-Driven High-Throughput Drug Screening on Patient-Derived Tumor Organoids: Accelerating Precision Medicine through Novel Mechanisms of Action
In the pursuit of precision medicine, the DrugVision.AI platform at UZA/UAntwerp leverages robotic high-throughput drug screening on...
Christophe Deben
Jan 301 min read
5
0
Development and validation of the Normalized Organoid Growth Rate (NOGR) metric in brightfield imaging-based assays
At DrugVision.ai , we're committed to pushing the boundaries of organoid drug screening by integrating cutting-edge technologies into our...
Christophe Deben
Dec 5, 20241 min read
50
0
Advancing Tumor Organoid Drug Screening
In our recent webinar, we delved into the transformative potential of live-cell imaging for advancing organoid drug screening. A key...
Christophe Deben
May 9, 20241 min read
79
0
Auranofin Repurposing for Lung and Pancreatic Cancer: Low CA12 Expression as a Marker of Sensitivity in Patient-Derived Organoids, with Potentiated Efficacy by AKT Inhibition.
This study embarked on an ambitious journey, utilizing twenty 384-well microplates, exploring 11 drug synergy combinations, and analyzing...
Christophe Deben
Jan 23, 20241 min read
43
0
Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer
In this translational study, we explore pancreatic ductal adenocarcinoma (PDAC) and its inherent treatment resistance, emphasizing the...
Christophe Deben
Jan 23, 20242 min read
16
0
Multiparametric Tumor Organoid Drug Screening Using Widefield Live-Cell Imaging for Bulk and Single-Organoid Analysis
In this publication, we introduce an innovative drug screening methodology using patient-derived tumor organoids. This paper focuses on...
Christophe Deben
Jan 23, 20242 min read
35
0
OrBITS: label-free and time-lapse monitoring of patient derivedorganoids for advanced drug screening
In our original manuscript, we delve into the foundational work behind the development of the OrBITS label-free organoid detection...
Christophe Deben
Jan 23, 20242 min read
36
0
Unlocking the Potential of Tumor Organoid Screening: Choosing Between Widefield and Confocal Live-Cell Imaging
Introduction Live-cell imaging techniques are emerging as an invaluable tool for drug development, offering unprecedented insights into...
Christophe Deben
Jan 12, 20243 min read
87
0
The Evolution of Preclinical Models in Drug Screening: From 2D Cell Lines to Patient-Derived Models
Introduction: Preclinical models are the cornerstone of drug screening and development, playing a pivotal role in the advancement of...
Christophe Deben
Dec 1, 20234 min read
95
0
bottom of page